Guide:Eye of Cthulhu strategies

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This means the page will walk you through a specific task, strategy, or enemy/boss fight.

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Status: Revised (This Guide got revised and is up to date!)

 "An ocular menace who only appears at night." 

The Eye of Cthulhu is one of the first bosses a player will encounter. The following are some hints, tips, and strategies to help defeat it.

Eye of CthulhuFirst Form

Map Icon

 Classic

 Expert

 Master

Statistics

Type	Boss
Environment	Surface + Night Space + Night
AI Type	Eye of Cthulhu AI
Damage	15/30/45
Max Life	2800/3640/4641
Defense	12
KB Resist	100%
Immune to

Drops

Coins	3 GC7 GC50 SC

Sounds

Hurt
Killed
Summon Servant
Entering second phase

• Internal NPC ID: 4

Eye of CthulhuSecond Form

Map Icon

 Classic

 Expert

 Master

Statistics

Type	Boss
Environment	Surface + Night Space + Night
AI Type	Eye of Cthulhu AI
Damage	2336 40 when below 145 health54 60 when below 185 health
Max Life	1400/28002366/36403016/4641
Defense	0
KB Resist	100%
Immune to

Drops

Coins	3 GC7 GC50 SC

• Item (Quantity)Rate
• Badger's Hat(Desktop, Console and Mobile versions)(when defeated on the same day
  as the Wall of Flesh)
  100%
• Binoculars
  2.5%
• Only in Corrupt worlds
• Demonite Ore (30-90)
  100%
• Unholy Arrow (20-50)
  100%
• Corrupt Seeds (1-3)
  100%
• Only in Crimson worlds
• Crimtane Ore (30-90)
  100%
• Crimson Seeds(Desktop, Console, Old-gen console and Mobile versions) (1-3)
  100%
• Lesser Healing Potion (5-15)
  100%
• Eye of Cthulhu Mask
  14.29%
• Eye of Cthulhu Trophy
  10%
• Treasure Bag(Desktop, Console and Mobile versions)(Eye of Cthulhu)
  100%
• Shield of Cthulhu(Desktop, Console and Mobile versions)
  100%
• Eye of Cthulhu Mask
  14.29%
• Binoculars
  3.33%
• Gold Coin (3)
  100%
• Only in Corrupt worlds
• Demonite Ore (30-90)
  100%
• Unholy Arrow (20-50)
  100%
• Corrupt Seeds (1-3)
  100%
• Only in Crimson worlds
• Crimtane Ore (30-90)
  100%
• Crimson Seeds(Desktop, Console, Old-gen console and Mobile versions) (1-3)
  100%
• Eye of Cthulhu Relic(Desktop, Console and Mobile versions)
  100%
• 0x33's Aviators(Desktop, Console and Mobile versions)
  100%
• Suspicious Grinning Eye(Desktop, Console and Mobile versions)
  25%

Sounds

Hurt
Killed
Charge
Chain charge

• Internal NPC ID: 4

Spawn Conditions

This content is transcluded from Eye of Cthulhu § Summoning.The Eye of Cthulhu can be summoned manually using a Suspicious Looking Eye at night (beginning at 7:30 PM in-game time). Only one Eye of Cthulhu can be summoned manually at a time.

It also has a 1/3 (33.33%) chance of spawning naturally each night, if the following conditions apply:

• The Eye of Cthulhu has not yet been defeated in the current world.
• At least one player in the world has at least 200 maximum health and more than 10 defense.
• At least four town NPCs are present in the world. While the Old Man, Traveling Merchant(Desktop, Console, Old-gen console and Mobile versions), and town pets(Desktop, Console and Mobile versions) count towards this total, the Skeleton Merchant(Desktop, Console and Mobile versions) does not.

If spawning naturally, its arrival is announced by the status message "You feel an evil presence watching you...". The Eye of Cthulhu spawns exactly 81 in-game minutes (at 8:51 PM) after this status message was displayed. If the player remains within a layer below the Surface for the entire night, or upon saving and exiting the world during singleplayer within the timespan of the boss spawning naturally will cause it to despawn.

If the player is sufficiently far underground, the Eye of Cthulhu will never spawn until they return to the Surface. Players will have to remain underground for most of the night to prevent the Eye of Cthulhu from spawning. Returning to the surface using a Magic Mirror, Recall Potion, or Potion of Return(Desktop, Console and Mobile versions) before night ends will cause it to spawn as usual.

The Fight

First Phase

During this phase the Eye will spend most of its time floating above you. It will summon Servants of Cthulhu which fly towards you to attack, much like Demon Eyes, but can also fly through walls and the ground.

After spawning 3 or 4 Servants, the Eye will charge at you, attempting to ram you 3 times before hovering once more, so be prepared to evade. It turns rather slowly as it charges, giving you time to prepare your next dodge. It can be helpful to begin to evade after the 3rd servant is spawned, as this will often allow you to dodge its first charge.

The Eye has 12 defense during this form, which negates 6 damage from every attack. As such, higher damage, lower speed weapons are more effective during the first form, such as the Musket or a bow. Alternatively a Sharktooth Necklace will allow faster-firing weapons to do excllent damage.

The Servants can be killed for Hearts, or, if there is enough room, the player can simply keep moving in one direction to avoid them. If the player gets swarmed by Servants, temporarily switching to a fast swinging weapon such as a sword will help get rid of them quickly. The Eye does contact damage, so be careful to watch it it while you kill the Servants.

Another strategy in this phase is to aim weapons at the pupil of the Eye, since that is where it spawns the Servants. That way, you can kill the servants and damage the Eye. Some piercing weapons can damage the eye multiple times, such as when firing straight into the air or when using a Spear at close range.

If not fighting on platforms, the Eye can go underground momentarily after a charge. Weapons like Whips and Spears can hit it through the ground; alternatively, debuffs such as On Fire! from Fire Arrows apply damage even when the boss is out of reach. Keep in mind that in  Desktop,  Console, and  Mobile versions, bosses have minimap icons to increase their visibility.

The second phase is triggered when the Eye reaches half health.

Second Phase

For the last half of the fight, the boss sheds its iris to reveal a fanged mouth. It moves slightly faster and deals more damage when it hits you but it also has no defense. It no longer summons servants in this phase. Instead, it charges 3 times, and then pauses for a few seconds during which you can attack freely.

Make sure to take advantage of its transformation sequence as much as possible, since it just spins in place for a few moments and you can still damage it.

Dodging is important during this phase, and should be given priority over doing damage. Hermes Boots or a variant of them are extremely useful. With a wide enough arena, running in a straight line while the Eye of Cthulhu does his quick charge is fast enough to avoid any damage, and allows the player to attack continuously.

Expert and Master Mode

In the first phase of the fight it spawns more servants and enters the second phase at 65% health instead of 50%, spawning 4-5 more Servants in that process. A piercing weapon is recommended for eliminating the Servants.

In this part of the fight, after the 3 normal lunges it will perform a brief series of extremely quick dashes at a steeper angle. As its health goes down, the Eye will use this ability more frequently, until its only action is to dart haphazardly back and forth, making it rather hard to hit. To avoid the lunges, Hermes Boots are practically required.

General Strategies

General Tips

This content is transcluded from Guide:Practical tips § Combat.

• For nocturnal bosses, starting the battle just after the sun sets (7:30 PM) will provide the maximum amount of time to defeat the boss. In Hardmode, the Moon Charm and/or Moon Stone and their upgrades are also useful at night.
• Boss battles can be won or lost before the battle ever starts. Choose your equipment and have it ready; find and/or make potions and placed buffs; use the highest-tier food you have available; set up an arena appropriate to the boss; learn the strategies for the boss you're facing.
• Prepare your Boss-fighting arena with adequate lighting, Campfires and Heart Lanterns for health regeneration, and Stars in Bottles for mana regeneration if you use magic. Bast Statues(Desktop, Console and Mobile versions) will provide a significant defensive boost. Garden Gnomes(Desktop, Console and Mobile versions) and (Desktop, Console and Mobile versions) (if underground) proper torch placement will reduce damage taken and increase damage dealt due to the luck. The Torch God's Favor(Desktop, Console and Mobile versions) helps with this. Honey pools can also be used for extra health regeneration.
• (Desktop, Console and Mobile versions) Sunflowers provide the Happy!(Desktop, Console and Mobile versions) buff to nearby players, which grants a +10% movement speed bonus and 17% reduction in enemy spawn rate.
• Always carry around a stack of the highest-tier healing potion available, as relying only on natural Health Regeneration is not a good idea. Depending on the game stage, this can include items such as Lesser Healing Potions or Honeyfins. On the  Desktop,  Console, and  Mobile versions, Restoration Potions are healing potions with a shorter cooldown.
  • Likewise carry mana potions, if you use Magic.
  • The Strange Brew(Desktop, Console and Mobile versions) is also an option, which yields very similar healing abilities to Healing Potion with added chances to trigger periods of invulnerability upon consumption.
  • On the  Old-gen console version and Nintendo 3DS version, Restoration Potions can save a slot, but will likewise trigger both cooldowns.
• It is suggested to build houses for the Dryad and the Nurse NPCs in your arena. The former casts the Dryad's Blessing(Desktop, Console and Mobile versions) buff, which increases your defense and provides you with a thorns-like effect, while the latter can heal and remove debuffs instantly, at the cost of some coins.
• Bosses are displayed on the Minimap: Follow the boss's icon to track it when you're struggling to find it. You can identify the boss icons by checking their respective wiki pages.
• Once you have freed the Mechanic in the Dungeon, you can use Wire to enhance your arena with Traps and helpful Heart and Star Statues. The former helps to damage the enemies, though be careful to set them up correctly in order not to hurt yourself during the battle. The latter will spawn heart and star pickups, respectively. Connect these devices to timers to activate them infinitely.
• In Hardmode, the Brand of the Inferno(Desktop, Console and Mobile versions) and Sergeant United Shield(Desktop, Console and Mobile versions) can be used to parry incoming contact damage.
• It may be useful to summon and kill the Eye of Cthulhu or King Slime before summoning any harder boss in order to spawn an extra one-use pool of Hearts. Note that this will prevent any Heart Statues from spawning new Hearts.
• Remember to use the Sharpening Station(Desktop, Console and Mobile versions), Ammo Box(Desktop, Console, Old-gen console and Mobile versions), Crystal Ball, Bewitching Table(Desktop, Console and Mobile versions), War Table(Desktop, Console and Mobile versions), and Slice of Cake(Desktop, Console and Mobile versions) before you go to explore or battle bosses/invasions. These will give boosts that are useful to have, with the first five being class-specific. They give Sharpened(Desktop, Console and Mobile versions), Ammo Box(Desktop, Console, Old-gen console and Mobile versions), Clairvoyance, Bewitched(Desktop, Console and Mobile versions), Strategist(Desktop, Console and Mobile versions), and Sugar Rush(Desktop, Console and Mobile versions), respectively.

Terrain preparation

A basic arena made for the Eye of Cthulhu.

An arena for the Eye of Cthulhu should be large enough to dodge and maneuver around in. The recommended size is just about the size of the screen, as the boss does not require a lot of mobility.

The simplest arena design consists of multiple rows of wooden platforms to have more room to jump and dodge. As the fight will be at night, add torches to improve visibility. Remember to adjust the distance between platforms depending on your jump height (this is 6 tiles at minimum, depending on which accessories you have), and consider placing some ladders (with platforms or rope) to aid your vertical movement.

Another design is a long, completely flat surface. This allows you to dodge the Eye by running to the left or the right with Swiftness Potions or Hermes Boots.

One of the easiest ways to defeat the Eye is a long, stretch of sand paired with Dunerider Boots(Desktop, Console and Mobile versions). Due to the speed boost gained on sand, it can be used as a surefire way to make dodging the Eye incredibly easy, making the fight trivial itself.

Gearing up

Armor

• (Desktop, Console and Mobile versions) Ninja Armor provides critical hit and speed boosts which benefit all classes. While it has less defense than metal armor, it will help end the fight faster and make dodging easier. It requires defeating King Slime, who can be farmed relatively easily by crafting Slime Crowns.
• (Desktop, Console and Mobile versions) Fossil armor's(Desktop, Console and Mobile versions) is the strongest set available for ranged weapons, but requires entering the dangerous Underground Desert.
• (Desktop, Console and Mobile versions) Gladiator Armor(Desktop, Console and Mobile versions) has high defense and provides Knockback immunity. It can be farmed from Hoplites in Marble Caves.
• The Wizard set which provides big buffs to magic weapon's stats. The Jungle Armor provides damage and mana bonuses, but requires entering the dangerous Underground Jungle.
• The Flinx Fur Coat(Desktop, Console and Mobile versions) is the only armor for summoners at this point.
• Out of armors made of Ore, Gold Armor or Platinum armor have the best defense, although they can be difficult to obtain this early.
  • A full set of Silver Armor or Tungsten Armor is easier to get at this point, and both are good choices for this fight. On the Nintendo 3DS version, the Boots of Ostara(3DS version) can be paired with Silver armor to complete the set bonus while increasing jump abilities, although using it with Tungsten armor will not grant the set bonus.
• On the Nintendo 3DS version, bones drop from skeletons, so Necro armor can be used here.

Weapons

In general, long-range piercing weapons are recommended, as they are able to take out Servants and hit the boss.

For Melee Users

Melee users options are fairly limited at this point, and melee weapons mostly serve as a way to take out the low-hp Servants of Cthulhu. Certain melee weapons are able to launch projectiles, but these may be difficult to come across.

• Long-range projectile swords can safely attack at a distance. These include the Enchanted Sword found rarely throughout the world, in Enchanted Sword Shrines, or in Golden Crates (Desktop, Console and Mobile versions), the Ice Blade found in Frozen Chests in the Ice biome, the Starfury found on Floating Islands, and the Blade of Grass (Desktop, Console and Mobile versions).
• Boomerangs can be of great use due to their long range, but missing with a boomerang can leave the player open to attack while it returns. A Trimarang(Desktop, Console and Mobile versions), Enchanted, Ice Boomerang or Thorn Chakram would be preferred.
• Yoyos(Desktop, Console and Mobile versions) are another type of melee weapon, and excel against the boss. The strongest available is the Amazon, although it requires venturing into the Underground Jungle early on. If a large amount of Demonite or Crimtane Ore has been obtained, a Malaise or Artery can be crafted. A Rally is readily available, but requires some luck and is weaker.
• A flail weapon such as the Flaming Mace(Desktop, Console and Mobile versions) or Ball O' Hurt can be useful due to their high speed and the ability to use the throw attack to deal high damage.
• If Demonite or Crimtane Ore has been found, the Light's Bane or Blood Butcherer are riskier but powerful options, and (Desktop, Console and Mobile versions) both have special abilities that aid in the fight (the Light's Bane spawning additional slashes and the Blood Butcherer adding a bleeding Debuff). Other non-projectile swords tend to do poorly against this boss besides clearing out the Servants.
• Spears can pierce through the Servants and do high damage to this boss, but can be risky due to short range. The safest spears include the Storm Spear(Desktop, Console and Mobile versions), found in the dangerous Underground Desert, and the The Rotted Fork, a powerful spear found in Crimson Hearts that (Desktop, Console and Mobile versions) emits a short shockwave. Other acceptable, but weaker, spears include the Trident found in Water Chests and the Swordfish, found by fishing in the Ocean.

For Ranged users

• Guns such as the Minishark and Boomstick are very effective against this boss, but they can be difficult to find, as the first requires the Arms Dealer to have arrived and the second is only found in the dangerous Underground Jungle. The Musket or The Undertaker are easier to find at this stage of the game, by breaking Shadow Orbs or Crimson Hearts. All guns besides the Musket benefit significantly from the Sharktooth Necklace or Silver or Tungsten Bullets during the first portion of the fight, when the boss's defense is higher.
• Bows are easy to craft and do good damage. Among craftable bows, the Gold Bow or Platinum Bow are the best bows available, unless the player happened to find a large quantity of Demonite or Crimtane Ore, in which case they can craft a Demon or Tendon Bow. The Blood Rain Bow(Desktop, Console and Mobile versions) is great in this fight, but can only be fished up during a Blood Moon and requires defeating a difficult mini-boss.
  • Frostburn Arrows deal the most damage to the boss itself and inflict Frostburn, but Jester's Arrows can kill the Servants and hurt the Eye in the same shot. Flaming Arrows are a good fallback option, in case your primary arrow choice runs out.
• (Desktop, Console and Mobile versions) Bone Javelins are cheap and powerful against the Eye of Cthulhu. They do heavy damage on-hit and add a damaging debuff that stacks. The Bone Throwing Knife(Desktop, Console and Mobile versions) is slightly weaker against the boss itself but pierces through the Servants.
• The Snowball Cannon is another fast firing weapon to use, doing decently against both phases.
• The Paintball Gun(Desktop, Console and Mobile versions), with its fast fire rate and high critical strike chance works well if you can manage to kill the Painter enough times.

For Magic users

Magic weapons are mainly good for beating on the boss itself, but can also be used to attack servants in a pinch. All magic weapons at this point are able to pierce through multiple enemies. More adventurous players can get their hands on much better weapons, and these should certainly be used for later "repeat engagements":

• Gem Staves simple to craft, and their long ranged piercing shots are a perfect fit for the boss battle. The strongest staves are the Diamond, Ruby staves, and Amber Staff(Desktop, Console and Mobile versions), while the worst are the Amethyst and Topaz staves, which have significantly less damage and piercing.
• The Thunder Zapper(Desktop, Console and Mobile versions) does great damage, but doesn't pierce and requires exploring the dangerous Underground Desert.
• The Crimson Rod is an excellent side-weapon, as its clouds can be set up to clear out the servants while also dealing steady damage to the boss. Its Corruption counterpart, theVilethorn, is not as helpful; it lacks some range, and does low damage. However, the lingering thorn can hit the boss and servants many times, and can even pass through walls to hit it. Both require exploring dangerous biomes and smashing either Crimson Hearts or Shadow Orbs.
• (Old-gen console and 3DS versions) The Space Gun, with its fast velocity and piercing propertie, is an excellent weapon, but requires a Meteorite to spawn after breaking a Shadow Orb or Crimson Heart. It works best with the set bonus of the Meteor Armor, which makes it not cost mana.
• (Old-gen console and 3DS versions) versions, a Water Bolt can be found on shelves in the Dungeon. If you get one, it can replace the Gem staves entirely. It will help to put solid-block walls around your arena, so you can make use of the Water Bolt's ricocheting projectiles.

For Summoners

There are very few summons available at this point, but the options available plus a good whip will be entirely sufficient enough to kill this boss without running out of time, especially in classic mode.

• The Flinx Staff(Desktop, Console and Mobile versions) will likely be the best summon weapon available at this point in the game. Alternatives include the Finch Staff(Desktop, Console and Mobile versions) and the Slime Staff. The Vampire Frog Staff(Desktop, Console and Mobile versions) is even stronger, though it may be difficult to obtain at this point as it requires defeating strong Blood Moon enemies.
• The Leather Whip(Desktop, Console and Mobile versions) is the most practical whip option at this point in the game, as it can be bought from the Zoologist(Desktop, Console and Mobile versions) NPC. The Snapthorn(Desktop, Console and Mobile versions) is much stronger, but requires exploring the dangerous Underground Jungle.

For (Old-gen console and 3DS versions) Throwing Users

Thrown weapons are at their best at this stage of the game, with a wide selection of effective weapons to use against this boss. Most of them are also cheap or easy to obtain, allowing the player to rack up stacks of thrown weapons.

• Grenades cause high damage and do damage in an area, but can damage the player. Since the Eye will be spawning Servants or charging at the player most of the time, it's difficult to keep a safe distance from the explosion. They can be purchased from the Demolitionist. A good strategy is to throw grenades behind you as you run away.
• Javelins are useful and deal good piercing damage, which makes them an amazing choice on the first phase.
• Molotov Cocktails avoid the danger of self-injury and work very well, especially in the second stage when Eye of Cthulhu will charge at you through the flaming puddles the Molotov Cocktails leave behind.
• Spiky Balls are very helpful in its second phase if you scatter them all over the floor of your arena.
• Shurikens are an effective weapon which can be bought from the Merchant. They will hit up to 4 times, allowing a well aimed shot to kill a Servant and hit the Eye twice - even three times, if it falls back through the boss. 500 or so are more than enough to defeat this boss with relative ease.
• Throwing Knives or Poisoned Knives perform similarly to Shurikens but do a lot more damage.

Accessories

• A Cloud in a Bottle or equivalents can aid in avoiding the rams, although this is less necessary with a good arena.
• The Fledgling Wings(Desktop, Console and Mobile versions) can be used to give the player short flight time and immunity to fall damage.
• A Grappling Hook is also very useful if you can grapple onto platforms above you quickly.
• Hermes Boots or equivalents help by making it easier to dodge the second phase's rams. In Expert Mode, these are almost required, as the Eye of Cthulhu will perform rapid dashing attacks.
  • Most movement modifiers do not increase the Boots' maximum speed. However, Magiluminescence(Desktop, Console and Mobile versions) has a +20% that stacks with the boots, making it much easier to outrun the dashes.
• The Shark Tooth Necklace(Desktop, Console and Mobile versions) will give a significant damage boost to most weapons available at the moment.
• If you find one, a Band of Regeneration can help speed up life regeneration, making lasting a longer fight easier. A Mana Regeneration Band should also be used for Magic players, as it regenerates Mana faster.

Any accessory with the Warding modifier will be useful if you come across one, and the extra four defense can be used to make up for lower-tier armor, like Iron Armor or Lead Armor.

Potions

• The most helpful potions are the Regeneration Potion, the Ironskin Potion, the Endurance Potion, Wrath Potion and the Swiftness Potion.
• Any food item that gives the Well Fed buff is welcomed, especially so for Expert Mode and Master Mode.
• Archery Potion significantly increases the damage output of bows.
• Magic Power Potion and Mana Regeneration Potion are good for magic users.

Other Tips

This content is transcluded from Eye of Cthulhu § Tips.

• The Eye of Cthulhu drops either Demonite or Crimtane Ore. While the corresponding set of armor and a number of tools additionally require Shadow Scales or Tissue Samples respectively—which the Eye does not drop—the sword, bow, axe, yoyo, and fishing pole can be crafted with only the bars.
• Due to the ease of crafting its summoning item and relatively low difficulty, farming the Eye of Cthulhu is one of the more effective ways of making money prior to Hardmode. It drops 3 GC / 7 GC50 SC up front, plus ores which can be sold as bars for twice (Demonite) or triple (Crimtane) that amount.
• The Eye of Cthulhu will only spawn randomly if a player has more than 10 defense. Taking defense-boosting equipment off before dusk can prevent it from spawning randomly.
• The boss looks at the player it will follow, which can be helpful information in multiplayer.
• It is most vulnerable during its transformation, because it neither moves nor attacks. However, there is only a brief window of opportunity for this.
• Because there are no location-based requirements for summoning, defeating multiple Eyes of Cthulhu in an area can be an effective setup for harder boss fights as the dropped Hearts can be picked up mid-fight as needed, though killing an Eye of Cthulhu for that purpose must be balanced with the time it takes away from killing a night-only boss.
• While it may seem that killing it on a Corruption-generated world would yield more money than doing so in a Crimson-generated world, as it will drop additional Unholy Arrows, Crimtane Ore and Bars sell for a 30% higher price than their Demonite counterparts, making them much more profitable.
• In singleplayer, the player can repeatedly pause the game using Autopause in order to properly aim at the Eye of Cthulhu during its dash attacks.

Specific Strategies

Slimy Saddle Strategy

An excellent strategy to beat the Eye in classic mode is to use the Slimy Saddle(Desktop, Console, Old-gen console and Mobile versions) and bounce on the eye while at the same time attacking it with a ranged weapon. The eye will move toward you and you will bounce on top of it continuously dealing damage. If you want to try this strategy, make sure you have some forms of preventing fall damage (i.e,) the Lucky Horseshoe, Grappling Hook, an Umbrella, or Cloud in a Bottle or Fledgling Wings

Magic Mirror Strategy

During the Second Phase, if you have your spawn point nearby, you can run one way and attack, and just when you think that the Eye is going to charge, use a Magic Mirror Ice Mirror or Recall Potion to teleport to spawn, now running the other way, evading the attack and being left to open fire.

Railway Strategy

Another great strategy is to build a long railway at least 400 blocks long, with each end hammered into a bumper. When the Eye spawns, start moving and continue to move whilst shooting at it. It may take longer than other methods, but it requires little mobility and you take minimal damage. Also, this strategy works better if in single player or all players in a multiplayer world are together in the same area.

Rail Loop Strategy

Building a rhombus with around 200 rails and going on a minecart will make it difficult for the boss to hit you, but it will also be hard to deal damage. A fast firing weapon with easily obtainable ammo (like Snowball Cannon or Minishark) will do best with this strategy. The fight will take longer than usual, but you will evade most of hits from the boss, and with a fast minecart, you might not even take damage. A Magic Missile or a Flamelash will help due to fast projectile speed and homing.

Pathway strategy

(For this strategy to work you need at least some form of fast running (e.g. Hermes Boots or its mount equivalent, the Fuzzy Carrot(Desktop, Console, Old-gen console and Mobile versions) ) )

This strategy requires 2 long pathways made out of Platforms in the sky, one on top of the other. Make sure that the platforms are parallel to each other and at least 4 blocks apart. Make sure the length of the 2 platforms are around 200 to 500 blocks. Place Campfires every 20 to 40 blocks, if you can afford it, place a Heart Lantern and/or a Star in a Bottle near the campfires.

Around the middle of the pathway, build a valid NPC house, then move the Nurse into it. If you are playing Multiplayer put a Bed in the house and set your spawn, so you can continue the fight even if you die.

When the fight begins, run along the 2 platforms attacking the Eye. Switch between the platforms to dodge attacks and avoid the Servants of Cthulhu. If you reach the end of a platform jump or fall to the other platform and switch directions. It is recommended that you use projectile-firing weapons such as bows, staves or magic books.

This strategy is slightly harder to execute the first time but if done effectively it will be easier in the future.